A Review: New Synthesis of Chalcone Derivatives and Their Applications

Abstract
Chalcones, also known as 1,3-diphenyl-2-propene-1-one, are organic substances composed of two aromatic rings connected by an unsaturated carbonyl group. These compounds belong to the flavonoid family and serve as precursors to other flavonoids found in a variety of plants. Naturally occurring in tea, fruits, vegetables, and spices, chalcones can be chemically synthesized through the Claisen-Schmidt condensation reaction, along with other methods like microwave irradiation and the Suzuki reaction. Chalcones and their derivatives exhibit a wide range of biological effects, including antibacterial, anticancer, and anti-inflammatory properties.

Author
Rzgar Farooq Rashid

DOI
https://doi.org/10.22034/crl.2025.480229.1427

ISSN
2645-4947

Publish Date: 2025-03-05